Affinity DataKi: 6.90E+3nMAssay Description:Inhibition of MKP5 (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
Affinity DataKi: 1.50E+5nMAssay Description:Inhibition of human MKP5 using DiFMUP as substrate after 5 mins by spectrophotometric plate reader analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.40E+5nMAssay Description:Inhibition of human MKP5 using DiFMUP as substrate after 5 mins by spectrophotometric plate reader analysisMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+5nMAssay Description:Inhibition of human MKP5 using DiFMUP as substrate after 5 mins by spectrophotometric plate reader analysisMore data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh
Curated by PubChem BioAssay
University Of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 136nMpH: 7.0 T: 2°CAssay Description:The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh
Curated by PubChem BioAssay
University Of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 158nMpH: 7.0 T: 2°CAssay Description:The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh
Curated by PubChem BioAssay
University Of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 184nMpH: 7.0 T: 2°CAssay Description:The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh
Curated by PubChem BioAssay
University Of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 190nMAssay Description:The MKP-1 Phosphatase Dose Response Confirmation and Secondary Selectivity/Specificity Assay has been Developed and Run at the University of Pittsbur...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh
Curated by PubChem BioAssay
University Of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 197nMpH: 7.0 T: 2°CAssay Description:The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh
Curated by PubChem BioAssay
University Of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 333nMAssay Description:The Cdc25B Phosphatase probe assessment MKP-1 dose response selectivity assay has been developed to test the phosphatase specificity of actives that ...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh
Curated by PubChem BioAssay
University Of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 423nMAssay Description:The Cdc25B Phosphatase probe assessment MKP-1 dose response selectivity assay has been developed to test the phosphatase specificity of actives that ...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh
Curated by PubChem BioAssay
University Of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 460nMAssay Description:Inhibition of recombinant MKP1More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh
Curated by PubChem BioAssay
University Of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 470nMAssay Description:Inhibition of recombinant MKP1More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh
Curated by PubChem BioAssay
University Of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 485nMAssay Description:The Cdc25B Phosphatase probe assessment MKP-1 dose response selectivity assay has been developed to test the phosphatase specificity of actives that ...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh
Curated by PubChem BioAssay
University Of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 520nMAssay Description:Inhibition of recombinant MKP1More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh
Curated by PubChem BioAssay
University Of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 743nMAssay Description:The MKP-1 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-1 inhibit...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh
Curated by PubChem BioAssay
University Of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 780nMAssay Description:Inhibition of recombinant MKP1More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Mus musculus)
Virginia Polytechnic Institute And State University
Curated by ChEMBL
Virginia Polytechnic Institute And State University
Curated by ChEMBL
Affinity DataIC50: 820nMAssay Description:Inhibition of histidine-tagged mouse MKP1 catalytic domain expressed in human Hela cellsMore data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Mus musculus)
Virginia Polytechnic Institute And State University
Curated by ChEMBL
Virginia Polytechnic Institute And State University
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of histidine-tagged mouse MKP1 catalytic domain expressed in human Hela cellsMore data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh
Curated by PubChem BioAssay
University Of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 1.13E+3nMpH: 7.0 T: 2°CAssay Description:The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh
Curated by PubChem BioAssay
University Of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 1.19E+3nMAssay Description:The MKP-1 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-1 inhibit...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh
Curated by PubChem BioAssay
University Of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 1.24E+3nMAssay Description:The MKP-1 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-1 inhibit...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh
Curated by PubChem BioAssay
University Of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 2.38E+3nMAssay Description:The Cdc25B Phosphatase probe assessment MKP-1 dose response selectivity assay has been developed to test the phosphatase specificity of actives that ...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh
Curated by PubChem BioAssay
University Of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of His-tagged DUSP1 catalytic domain (152 to 323 residues) (unknown origin) using DiFMUP as substrate incubated for 30 mins by spectrofluo...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh
Curated by PubChem BioAssay
University Of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of recombinant MKP1More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 15(Homo sapiens (Human))
Indiana University School Of Medicine
Curated by ChEMBL
Indiana University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of recombinant VHX (unknown origin) using pNPP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+3nMAssay Description:For selectivity studies, the PTPs, including LYP, mPTPA, SHP1-D1C, PTP1B, LMPTP, VHR, Laforin and PTPα-D1D2 were expressed and purified from E. ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of MKP5 (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh
Curated by PubChem BioAssay
University Of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 3.49E+3nMpH: 7.0 T: 2°CAssay Description:The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh
Curated by PubChem BioAssay
University Of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 4.50E+3nMpH: 7.0 T: 2°CAssay Description:The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 15(Homo sapiens (Human))
Indiana University School Of Medicine
Curated by ChEMBL
Indiana University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of recombinant VHX (unknown origin) using pNPP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh
Curated by PubChem BioAssay
University Of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 4.61E+3nMAssay Description:The Cdc25B Phosphatase probe assessment MKP-1 dose response selectivity assay has been developed to test the phosphatase specificity of actives that ...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh
Curated by PubChem BioAssay
University Of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of His-tagged DUSP1 catalytic domain (152 to 323 residues) (unknown origin) using DiFMUP as substrate incubated for 30 mins by spectrofluo...More data for this Ligand-Target Pair
Affinity DataIC50: 5.70E+3nMpH: 7.0Assay Description:Inhibition of MKP5 (unknown origin) using pNPP as substrate at pH 7 at 25 degC by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh
Curated by PubChem BioAssay
University Of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 6.39E+3nMAssay Description:The MKP-1 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-1 inhibit...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh
Curated by PubChem BioAssay
University Of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 6.53E+3nMpH: 7.0 T: 2°CAssay Description:The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh
Curated by PubChem BioAssay
University Of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of His-tagged DUSP1 catalytic domain (152 to 323 residues) (unknown origin) using DiFMUP as substrate incubated for 30 mins by spectrofluo...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh
Curated by PubChem BioAssay
University Of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 6.96E+3nMAssay Description:The MKP-1 dose response Active/Probe assessment-Catalase assay has been developed to evaluate the effects of adding 100 U/mL of Catalase on the MKP-1...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh
Curated by PubChem BioAssay
University Of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 6.96E+3nMAssay Description:The MKP-1 dose response Active/Probe assessment-DTT assay has been developed to evaluate the effects of increased DTT concentration on the MKP-1 inhi...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh
Curated by PubChem BioAssay
University Of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 7.02E+3nMAssay Description:The Cdc25B Phosphatase probe assessment MKP-1 dose response selectivity assay has been developed to test the phosphatase specificity of actives that ...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh
Curated by PubChem BioAssay
University Of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 7.34E+3nMAssay Description:The MKP-1 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-1 inhibit...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh
Curated by PubChem BioAssay
University Of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 7.66E+3nMpH: 7.0 T: 2°CAssay Description:The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh
Curated by PubChem BioAssay
University Of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of His-tagged DUSP1 catalytic domain (152 to 323 residues) (unknown origin) using DiFMUP as substrate incubated for 30 mins by spectrofluo...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh
Curated by PubChem BioAssay
University Of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of His-tagged DUSP1 catalytic domain (152 to 323 residues) (unknown origin) using DiFMUP as substrate incubated for 30 mins by spectrofluo...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Mus musculus)
Virginia Polytechnic Institute And State University
Curated by ChEMBL
Virginia Polytechnic Institute And State University
Curated by ChEMBL
Affinity DataIC50: 8.45E+3nMAssay Description:Inhibition of histidine-tagged mouse MKP1 catalytic domain expressed in human Hela cellsMore data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh
Curated by PubChem BioAssay
University Of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of His-tagged DUSP1 catalytic domain (152 to 323 residues) (unknown origin) using DiFMUP as substrate incubated for 30 mins by spectrofluo...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh
Curated by PubChem BioAssay
University Of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 8.75E+3nMAssay Description:The Cdc25B Phosphatase probe assessment MKP-1 dose response selectivity assay has been developed to test the phosphatase specificity of actives that ...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh
Curated by PubChem BioAssay
University Of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 8.85E+3nMpH: 7.0 T: 2°CAssay Description:The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Mus musculus)
Virginia Polytechnic Institute And State University
Curated by ChEMBL
Virginia Polytechnic Institute And State University
Curated by ChEMBL
Affinity DataIC50: 9.37E+3nMAssay Description:Inhibition of histidine-tagged mouse MKP1 catalytic domain expressed in human Hela cellsMore data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh
Curated by PubChem BioAssay
University Of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: 9.38E+3nMpH: 7.0 T: 2°CAssay Description:The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...More data for this Ligand-Target Pair